Day: January 28, 2019

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I Really Want To See This

And I don’t care what you say.

Laurel & Hardy, one of the world’s great comedy teams, set out on a variety hall tour of Britain in 1953. Diminished by age and with their golden era as the kings of Hollywood comedy now behind them, they face an uncertain future. As the charm and beauty of their performances shines through, they re-connect with their adoring fans.

The tour becomes a hit, but Stan & Ollie can’t quite shake the specter of Laurel and Hardy’s past; the long-buried ghosts, coupled with Oliver’s failing health, start to threaten their precious partnership. A portrait of the most tender and poignant of creative marriages, they are aware that they may be approaching their swan song, trying to rediscover just how much they mean to each other.

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Thief Or Hermit?

Did you ever think to yourself “fuck this shit! I’m checking out of society…”? Well, this fucker up in Maine did, and he checked out for 27 years until he got caught. he basically set up camp in the woods not far from some cabins around a lake. To get by he stole food and fuel from the nearby cabins. He kinda freaked out the locals, because not one ever saw him.

Eventually he was caught in the act and went to jail for a short period of time. He just couldn’t handle society. The sad thing is that the author has now made this guy the most popular man in Maine, and it wouldn’t surprise me if someone makes a movie out of this.

I basically told you the majority of the book, but it’s an interesting story and a fast read if you want to delve a little deeper.

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Gum Disease May Cause Alzheimer’s

You bastards better keep flossing! According to NewScientist …

If you bled when you brushed your teeth this morning, you might want to get that seen to. We may finally have found the long-elusive cause of Alzheimer’s disease: Porphyromonas gingivalis, the key bacteria in chronic gum disease.

That’s bad, as gum disease affects around a third of all people. But the good news is that a drug that blocks the main toxins of P. gingivalis is entering major clinical trials this year, and research published today shows it might stop and even reverse Alzheimer’s. There could even be a vaccine.

Multiple research teams have been investigating P. gingivalis, and have so far found that it invades and inflames brain regions affected by Alzheimer’s; that gum infections can worsen symptoms in mice genetically engineered to have Alzheimer’s; and that it can cause Alzheimer’s-like brain inflammation, neural damage, and amyloid plaques in healthy mice.

“When science converges from multiple independent laboratories like this, it is very compelling,” says Casey Lynch of Cortexyme, a pharmaceutical firm in San Francisco, California.

In the new study, Cortexyme have now reported finding the toxic enzymes – called gingipains – that P. gingivalis uses to feed on human tissue in 96 per cent of the 54 Alzheimer’s brain samples they looked at, and found the bacteria themselves in all three Alzheimer’s brains whose DNA they examined.

Full article here.